{{Rsnum
|rsid=374748
|Gene=FBN2
|Chromosome=5
|position=128363682
|Orientation=plus
|GMAF=0.1276
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=FBN2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 73.5 | 25.7 | 0.9
| HCB | 100.0 | 0.0 | 0.0
| JPT | 95.6 | 4.4 | 0.0
| YRI | 46.3 | 43.5 | 10.2
| ASW | 49.1 | 43.9 | 7.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 81.2 | 18.8 | 0.0
| LWK | 57.3 | 36.4 | 6.4
| MEX | 77.6 | 20.7 | 1.7
| MKK | 68.6 | 25.6 | 5.8
| TSI | 76.5 | 22.5 | 1.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19553259
|Trait=Obesity (extreme)
|Title=Common BMI-associated variants confer risk of extreme obesity
|RiskAllele=G
|Pval=0.000004
|OR=1.47
|ORtxt=[1.25-1.73]
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs374748
|overall_frequency_n=109
|overall_frequency_d=124
|overall_frequency=0.879032
|n_genomes=51
|n_genomes_annotated=0
|n_haplomes=92
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}