{{Rsnum
|rsid=3747517
|Gene=IFIH1
|Chromosome=2
|position=162272314
|Orientation=minus
|GMAF=0.3912
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=IFIH1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 2.7 | 36.3 | 61.1
| HCB | 48.9 | 42.3 | 8.8
| JPT | 38.9 | 47.8 | 13.3
| YRI | 13.0 | 50.0 | 37.0
| ASW | 19.3 | 36.8 | 43.9
| CHB | 48.9 | 42.3 | 8.8
| CHD | 46.8 | 46.8 | 6.4
| GIH | 11.0 | 44.0 | 45.0
| LWK | 19.1 | 47.3 | 33.6
| MEX | 6.9 | 27.6 | 65.5
| MKK | 28.8 | 46.2 | 25.0
| TSI | 4.0 | 44.6 | 51.5
| HapMapRevision=28
}}{{PMID Auto
|PMID=19450885
|Title=Multiple sclerosis and polymorphisms of innate pattern recognition receptors TLR1-10, NOD1-2, DDX58, and IFIH1
}}

{{PMID Auto
|PMID=18071670
|Title=The association between the IFIH1 locus and type 1 diabetes.
}}

{{PMID Auto
|PMID=18927125
|Title=IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells.
|OA=1
}}

{{PMID Auto
|PMID=19264985
|Title=Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=19374514
|Title=Expression and alternative splicing of folate pathway genes in HapMap lymphoblastoid cell lines.
|OA=1
}}

{{PMID Auto
|PMID=19956101
|Title=Overview of the Rapid Response data.
|OA=1
}}

{{PMID Auto
|PMID=19956106
|Title=Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.
|OA=1
}}

{{PMID Auto
|PMID=19956109
|Title=The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.
|OA=1
}}

{{PMID Auto
|PMID=22053898
|Title=IFIH1 gene polymorphisms in type 1 diabetes: genetic association analysis and genotype-phenotype correlation in Chinese Han population.
}}

{{PMID Auto
|PMID=22152027
|Title=Genetic variants in IFIH1 play opposite roles in the pathogenesis of psoriasis and chronic periodontitis.
}}

{{GET Evidence
|gene=IFIH1
|aa_change=His843Arg
|aa_change_short=H843R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3747517
|overall_frequency_n=7442
|overall_frequency_d=10758
|overall_frequency=0.691764
|n_genomes=49
|n_genomes_annotated=0
|n_haplomes=74
|n_articles=0
|n_articles_annotated=0
|nblosum100=1
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=22789000
|Title=Polymorphisms in the interferon-induced helicase (IFIH1) locus and susceptibility to Addison's disease
}}

{{PMID Auto
|PMID=23535865
|Title=Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility
}}

{{PMID Auto
|PMID=24960033
|Title=Association of innate immune IFIH1 gene polymorphisms with dilated cardiomyopathy in a Chinese population
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}