{{Rsnum
|rsid=3747742
|Chromosome=6
|Orientation=plus
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene=TREML2
|position=41194780
|Gene_s=TREML2
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 8.8 | 38.9 | 52.2
| HCB | 15.3 | 46.7 | 38.0
| JPT | 8.0 | 43.4 | 48.7
| YRI | 2.0 | 36.7 | 61.2
| ASW | 3.5 | 33.3 | 63.2
| CHB | 15.3 | 46.7 | 38.0
| CHD | 10.1 | 37.6 | 52.3
| GIH | 23.8 | 43.6 | 32.7
| LWK | 6.4 | 43.6 | 50.0
| MEX | 17.2 | 43.1 | 39.7
| MKK | 9.6 | 41.0 | 49.4
| TSI | 10.8 | 40.2 | 49.0
| HapMapRevision=28
}}[[rs3747742]] is a [[SNP]] in the Triggering receptor expressed on myeloid cells-like 2 [[TREML2]] gene.

See the genotype page  [[rs3747742(G;G)]].

The minor allele of [[rs3747742]] has been reported in a large study (IGAP) to be associated with a reduced risk of [[Alzheimer's Disease]]. The protective allele is (G). The odds ratio associated with heterozygotes and homozygotes of the G allele versus the A allele is 0.93 (CI 0.89-0.96).
{{PMID|24439484}}  Missense variant in TREML2 protects against Alzheimer's disease

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