{{Rsnum
|rsid=3748816
|Gene=MMEL1
|Chromosome=1
|position=2595307
|Orientation=minus
|GMAF=0.477
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=MMEL1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 13.3 | 40.7 | 46.0
| HCB | 24.1 | 57.7 | 18.2
| JPT | 23.9 | 51.3 | 24.8
| YRI | 56.5 | 38.1 | 5.4
| ASW | 49.1 | 36.8 | 14.0
| CHB | 24.1 | 57.7 | 18.2
| CHD | 27.5 | 54.1 | 18.3
| GIH | 22.8 | 46.5 | 30.7
| LWK | 50.0 | 37.3 | 12.7
| MEX | 17.2 | 53.4 | 29.3
| MKK | 44.9 | 42.3 | 12.8
| TSI | 5.9 | 41.2 | 52.9
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=20190752
|Trait=Celiac disease
|Title=Multiple common variants for celiac disease influencing immune gene expression
|RiskAllele=
|Pval=3E-9
|OR=1.12
|ORtxt=[1.09-1.18]
|OA=1
}}

{{PMID Auto
|PMID=20574445
|Title=A non-synonymous SNP within the membrane metalloendopeptidase-like 1 gene (MMEL1) is associated with multiple sclerosis.
|OA=1
}}

The G allele is associated with 1.3 times higher odds of [[primary biliary cirrhosis]]. {{PMID|20639879|OA=1
}}

{{PMID|21383967|OA=1
}} Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

{{GET Evidence
|gene=MMEL1
|aa_change=Met509Thr
|aa_change_short=M509T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3748816
|overall_frequency_n=69
|overall_frequency_d=128
|overall_frequency=0.539062
|n_genomes=41
|n_genomes_annotated=0
|n_haplomes=55
|n_articles=0
|n_articles_annotated=0
|nblosum100=2
|autoscore=0
|webscore=N
}}

[[Primary Biliary Cirrhosis: Preliminary Research]]

{{PMID Auto
|PMID=22521342
|Title=Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci.
|OA=1
}}

{{PMID Auto
|PMID=22922229
|Title=Seven newly identified loci for autoimmune thyroid disease.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}