{{Rsnum
|rsid=3749380
|Gene=GRM7
|Chromosome=3
|position=6861610
|Orientation=minus
|ReferenceAllele=C
|GMAF=0.3765
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=GRM7
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 19.5 | 42.5 | 38.1
| HCB | 11.7 | 40.9 | 47.4
| JPT | 17.7 | 42.5 | 39.8
| YRI | 8.8 | 44.9 | 46.3
| ASW | 14.0 | 57.9 | 28.1
| CHB | 11.7 | 40.9 | 47.4
| CHD | 7.3 | 44.0 | 48.6
| GIH | 31.7 | 51.5 | 16.8
| LWK | 11.8 | 42.7 | 45.5
| MEX | 15.5 | 44.8 | 39.7
| MKK | 19.9 | 47.4 | 32.7
| TSI | 17.6 | 49.0 | 33.3
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19165232
|Trait=Panic disorder
|Title=Genome-wide association study of panic disorder in the Japanese population
|RiskAllele=
|Pval=0.000002
|OR=NR
|ORtxt=NR
}}

{{PharmGKB
|RSID=rs3749380
|Name_s=
|Gene_s=GRM7
|Feature=
|Evidence=PubMed ID:19165232; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association study of panic disorder in the Japanese population. (Initial Sample Size: 200 Japanese cases, 200 Japanese controls; Replication Sample Size: NR); (Region: 3p26.1; Reported Gene(s): GRM7; Risk Allele: rs3749380-?); (p-value= 0.000002).This variant is associated with Panic disorder.
|Drugs=
|Drug Classes=
|Diseases=Panic Disorder
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740058
}}

{{PMID Auto
|PMID=18329248
|Title=A polymorphism of the metabotropic glutamate receptor mGluR7 (GRM7) gene is associated with schizophrenia.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3749380
|overall_frequency_n=3850
|overall_frequency_d=10758
|overall_frequency=0.357873
|n_genomes=37
|n_genomes_annotated=0
|n_haplomes=49
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}