{{Rsnum
|rsid=3750817
|Gene=FGFR2
|Chromosome=10
|position=123332577
|Orientation=plus
|GMAF=0.3379
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}
{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 42.5 | 43.4 | 14.2
| HCB | 21.9 | 51.8 | 26.3
| JPT | 20.4 | 49.6 | 30.1
| YRI | 97.3 | 2.7 | 0.0
| ASW | 91.2 | 8.8 | 0.0
| CHB | 21.9 | 51.8 | 26.3
| CHD | 16.5 | 53.2 | 30.3
| GIH | 30.7 | 52.5 | 16.8
| LWK | 93.6 | 6.4 | 0.0
| MEX | 36.2 | 50.0 | 13.8
| MKK | 85.9 | 14.1 | 0.0
| TSI | 45.1 | 43.1 | 11.8
| HapMapRevision=28
}}[[rs3750817]] is a SNP in the fibroblast growth factor receptor 2 [[FGFR2]] gene.

A study of 2,166 invasive [[breast cancer]] cases concluded that carriers of a [[rs3750817]](T) allele had lower risk for cancer, with an estimated per-minor-allele odds ratio of 0.78. Success with hormone therapy to treat postmenopausal symptoms also correlated with the number of [[rs3750817]](T) alleles. 
{{PMID|19861516|OA=1
}}

{{PMID Auto
|PMID=20056625
|Title=Variation in the FGFR2 gene and the effect of a low-fat dietary pattern on invasive breast cancer
|OA=1
}}

{{PMID Auto
|PMID=21702935
|Title=Genetic variants in the MRPS30 region and postmenopausal breast cancer risk
|OA=1
}}

{{PMID Auto
|PMID=21791674
|Title=Interactions Between Genetic Variants and Breast Cancer Risk Factors in the Breast and Prostate Cancer Cohort Consortium
|OA=1
}}

{{PMID Auto
|PMID=21822685
|Title=Genetic variants of fibroblast growth factor receptor 2 (FGFR2) are associated with breast cancer risk in Chinese women of the Han nationality
}}

{{PMID|18285324|OA=1
}} Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk.

{{PMID Auto GWAS
  |PMID=22951594
  |Trait=Breast cancer
  |Title=A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
  |RiskAllele=T
  |Pval=8E-8
  |OR=1.22
  |ORtxt=[NR]
  }}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}