{{Rsnum
|rsid=3753380
|Gene=PTGFR
|Chromosome=1
|position=78490747
|Orientation=minus
|GMAF=0.241
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PTGFR
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 10.7 | 45.5 | 43.8
| HCB | 11.0 | 36.8 | 52.2
| JPT | 10.8 | 49.5 | 39.6
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 16.1 | 83.9
| CHB | 11.0 | 36.8 | 52.2
| CHD | 1.9 | 42.6 | 55.6
| GIH | 7.0 | 39.0 | 54.0
| LWK | 0.9 | 1.8 | 97.3
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 14.8 | 85.2
| TSI | 12.9 | 40.6 | 46.5
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs3753380
|Name_s=
|Gene_s=PTGFR
|Feature=
|Evidence=PubMed ID:17467803
|Annotation=lower response allele: C; phenotype: change in interocular pressure; study size: 100; study population: healthy Japanese subjects with no history of eye disease; description: change in interocular pressure: CC, 20.3%&#177;1.5%; CT + TT, 15.6%&#177;1.2%; P = 0.0316; T allele associate with lower transcriptional activity; type of association: CO
|Drugs=latanoprost
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA165111467
}}

{{PMID Auto
|PMID=22060278
|Title=Lack of association between polymorphisms in the prostaglandin F(2alpha) receptor and solute carrier organic anion transporter family 2A1 genes and intraocular pressure response to prostaglandin analogs.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3753380
|overall_frequency_n=102
|overall_frequency_d=128
|overall_frequency=0.796875
|n_genomes=52
|n_genomes_annotated=0
|n_haplomes=88
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=24457363
|Title=Association between genetic polymorphisms of the prostaglandin F2α receptor gene, and response to latanoprost in patients with glaucoma and ocular hypertension
}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}