{{Rsnum
|rsid=3753394
|Gene=CFH
|Chromosome=1
|position=196651787
|Orientation=plus
|GMAF=0.2851
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CFH
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 54.9 | 34.5 | 10.6
| HCB | 21.2 | 46.0 | 32.8
| JPT | 23.0 | 52.2 | 24.8
| YRI | 93.8 | 6.2 | 0.0
| ASW | 80.7 | 19.3 | 0.0
| CHB | 21.2 | 46.0 | 32.8
| CHD | 19.3 | 54.1 | 26.6
| GIH | 60.4 | 36.6 | 3.0
| LWK | 97.3 | 2.7 | 0.0
| MEX | 49.1 | 35.1 | 15.8
| MKK | 82.1 | 16.7 | 1.3
| TSI | 49.0 | 39.2 | 11.8
| HapMapRevision=28
}}

linked to blindness in old age

[[rs3753394]] carries a significantly increased risk for exudative AMD.
{{PMID|17167412}}

linked to [[rs3753394]], [[rs800292]], [[rs1061147]], [[rs1061170]], [[rs380390]], and [[rs1329428]]

Significant associations were detected for [[AMD]] with 
[[rs3753394]]
[[rs800292]]
[[rs1329428]]

A haplotype of [[rs1061170]] [[rs3753394]] [[rs800292]] [[rs1329428]] (TGTC) was found to confer a significantly increased likelihood of exudative AMD

[[CFH]] variations appear to contribute to [[ARMD]] in Caucasians, but not in Japanese {{PMID|16710702}}

{{PMID Auto
|PMID=19162324
|Title=Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis
}}

{{PMID|18421087}} Multiple gene polymorphisms in the complement factor h gene are associated with exudative age-related macular degeneration in chinese.

{{PMID|18483746|OA=1
}} Plasma therapy in atypical haemolytic uremic syndrome: lessons from a family with a factor H mutation.

{{PMID|18515590}} Association analysis of CFH, C2, BF, and HTRA1 gene polymorphisms in Chinese patients with polypoidal choroidal vasculopathy.

{{PMID|19026761|OA=1
}} Molecular pathology of age-related macular degeneration.

{{PMID|19187823}} Coding variant I62V in the complement factor H gene is strongly associated with polypoidal choroidal vasculopathy.

{{PMID|19861685|OA=1
}} Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome.

{{PMID|20161815|OA=1
}} SERPING1 polymorphisms in polypoidal choroidal vasculopathy.

{{PMID|21111031}} Correlation of complement factor H gene polymorphisms with exudative age-related macular degeneration in a Chinese cohort.

{{PMID|22035603|OA=1
}} Plasma biomarkers of oxidative stress and genetic variants in age-related macular degeneration.

{{PMID Auto GWAS
  |PMID=23028341
  |Trait=Complement C3 and C4 levels
  |Title=Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects.
  |RiskAllele=C
  |Pval=7E-11
  |OR=.05
  |ORtxt=[0.030-0.070] g/L decrease
  |OA=1
}}

{{PMID Auto
|PMID=23919682
|Title=Complement alternative pathway genetic variation and Dengue infection in the Thai population
|OA=1
}}

{{PMID Auto
|PMID=24365176
|Title=Common variants in the complement factor H gene confer genetic susceptibility to central serous chorioretinopathy
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}