{{Rsnum
|rsid=3755351
|Gene=ADD2
|Chromosome=2
|position=70747758
|Orientation=minus
|GMAF=0.3448
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=ADD2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 12.4 | 45.1 | 42.5
| HCB | 10.2 | 47.4 | 42.3
| JPT | 8.0 | 31.0 | 61.1
| YRI | 13.6 | 48.3 | 38.1
| ASW | 5.3 | 52.6 | 42.1
| CHB | 10.2 | 47.4 | 42.3
| CHD | 6.5 | 49.1 | 44.4
| GIH | 6.9 | 41.6 | 51.5
| LWK | 11.8 | 47.3 | 40.9
| MEX | 10.3 | 48.3 | 41.4
| MKK | 11.5 | 53.8 | 34.6
| TSI | 15.7 | 51.0 | 33.3
| HapMapRevision=28
}}
[[rs3755351]], a SNP in the [[ADD2]] gene, was associated with risk for [[hypertension]] in a study involving 1,500+ Japanese patients. The odds ratio associated with the risk allele, [[rs3755351(C)]], which is also the most common allele, is 1.30 (CI: 1.15 - 1.46, p = 0.00002). {{PMID|18003638}}

Note that a neighboring [[ADD2]] SNP in close (r2 of 0.806) proximity, [[rs17006246]], was associated with [[hypertension]] in a diabetes study {{PMID|17463246}}; however, in this case, it was in "the opposite direction of effect". This discrepancy has not been resolved. {{PMID|18003638}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}