{{Rsnum
|rsid=3765310
|Gene=ALDH5A1
|Chromosome=6
|position=24503369
|Orientation=plus
|GMAF=0.045
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ALDH5A1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 91.2 | 8.8 | 0.0
| HCB | 88.8 | 11.2 | 0.0
| JPT | 73.9 | 26.1 | 0.0
| YRI | 96.6 | 3.4 | 0.0
| ASW | 94.7 | 5.3 | 0.0
| CHB | 88.8 | 11.2 | 0.0
| CHD | 79.8 | 20.2 | 0.0
| GIH | 80.8 | 17.2 | 2.0
| LWK | 86.2 | 13.8 | 0.0
| MEX | 91.4 | 8.6 | 0.0
| MKK | 89.7 | 10.3 | 0.0
| TSI | 93.1 | 6.9 | 0.0
| HapMapRevision=28
}}Mutational spectrum of the succinate semialdehyde dehydrogenase (ALDH5A1) gene and functional analysis of 27 novel disease-causing mutations in patients with SSADH deficiency.{{PMID|14635103}} Reduced SSADH activity with T variant (48% of normal).

{{PMID Auto
|PMID=15514892
|Title=A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States.
|OA=1
}}

{{PMID Auto
|PMID=19164088
|Title=Comparative genomics of aldehyde dehydrogenase 5a1 (succinate semialdehyde dehydrogenase) and accumulation of gamma-hydroxybutyrate associated with its deficiency.
|OA=1
}}

{{GET Evidence
|gene=ALDH5A1
|aa_change=Pro182Leu
|aa_change_short=P182L
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3765310
|overall_frequency_n=282
|overall_frequency_d=10758
|overall_frequency=0.026213
|n_genomes=2
|n_genomes_annotated=0
|n_haplomes=2
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=7
|autoscore=3
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}