{{Rsnum
|rsid=3767155
|Gene=ALPL
|Chromosome=1
|position=21558702
|Orientation=minus
|GMAF=0.2934
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=ALPL
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 9.7 | 46.0 | 44.2
| HCB | 13.2 | 44.9 | 41.9
| JPT | 5.3 | 41.6 | 53.1
| YRI | 2.7 | 27.9 | 69.4
| ASW | 8.8 | 42.1 | 49.1
| CHB | 13.2 | 44.9 | 41.9
| CHD | 10.1 | 40.4 | 49.5
| GIH | 25.7 | 46.5 | 27.7
| LWK | 2.7 | 18.2 | 79.1
| MEX | 12.3 | 54.4 | 33.3
| MKK | 1.3 | 18.6 | 80.1
| TSI | 9.8 | 40.2 | 50.0
| HapMapRevision=28
}}{{PMID|17195227}} A study of 201 Canadian [[ankylosing spondylitis]] families concluded the ALPL (TNAP) haplotype G-G-T for SNPs [[rs3767155]]-[[rs3738099]]-[[rs1780329]], respectively, is significantly associated with the disease but only in men.

{{PMID|18769922}} A study of 353 Chinese ankylosing spondylitis patients found no significant difference in allele, genotype or haplotype frequencies for this SNP in either case-control or family-based association studies, which indicated that the TNAP (also known as ALPL) gene is unlikely to play a major role in the susceptibility to ankylosing spondylitis in the Chinese Han population.

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}