{{Rsnum
|rsid=3768687
|Gene=ACVR2A
|Chromosome=2
|position=147914451
|Orientation=minus
|GMAF=0.3875
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=ACVR2A
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 4.8 | 52.4 | 42.9
| HCB | 12.2 | 65.9 | 22.0
| JPT | 20.5 | 54.5 | 25.0
| YRI | 0.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 12.2 | 65.9 | 22.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}This SNP is located on chromosome 2q22-23, in the activin receptor type 2 gene ([[ACVR2A]]) gene.

A study of 1139 Norwegian women with one or more pre-eclamptic pregnancies and 2269 controls (women with normal pregnancies) identified four SNPs in this region ([[rs1424941]], [[rs1014064]], [[rs2161983]] and [[rs3768687]]) as associated with higher risk for [[pre-eclampsia]].

{{PMID Auto
|PMID=18781190
|Title=Association between the candidate susceptibility gene ACVR2A on chromosome 2q22 and pre-eclampsia in a large Norwegian population-based study (the HUNT study).
|OA=1
}}

{{PMID Auto
|PMID=19126782
|Title=Genetic association of the activin A receptor gene (ACVR2A) and pre-eclampsia.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}