{{Rsnum
|rsid=3775289
|Gene=DCK
|Chromosome=4
|position=70996957
|Orientation=minus
|GMAF=0.1928
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=DCK
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 14.3 | 85.7
| HCB | 0.7 | 5.8 | 93.4
| JPT | 2.7 | 8.0 | 89.4
| YRI | 54.4 | 37.4 | 8.2
| ASW | 43.9 | 43.9 | 12.3
| CHB | 0.7 | 5.8 | 93.4
| CHD | 0.0 | 9.3 | 90.7
| GIH | 0.0 | 6.9 | 93.1
| LWK | 36.1 | 50.9 | 13.0
| MEX | 3.4 | 10.3 | 86.2
| MKK | 38.5 | 45.5 | 16.0
| TSI | 1.0 | 14.9 | 84.2
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs3775289
|Name_s=DCK:IVS1-1110T>C
|Gene_s=DCK
|Feature=Intron
|Evidence=PubMed ID:15224082
|Annotation=Risk or phenotype-associated allele: None. Phenotype: Variants identified in a screen of 13 genes involved in the gemcitabine drug metabolic pathway. For the intronic DCK:IVS1-1110T>C SNP, the C allele was not observed among the Europeans and Africans interrogated in this study. There was no significant difference between ethnic groups in genotype frequency distribution (p > 0.05). Study size: 179. Study population/ethnicity: Healthy, unrelated blood donors of European (n = 90) and African (n = 89) descent. Significance metric(s): Not significant, p > 0.05. Type of association: GN.
|Drugs=gemcitabine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA165110716
}}

{{PMID|19898621|OA=1
}} Gemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkers.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3775289
|overall_frequency_n=91
|overall_frequency_d=124
|overall_frequency=0.733871
|n_genomes=43
|n_genomes_annotated=0
|n_haplomes=74
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}