{{Rsnum
|rsid=3780412
|Gene=SLC1A1
|Chromosome=9
|position=4572480
|Orientation=minus
|GMAF=0.4137
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SLC1A1,SPATA6L
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 31.2 | 46.4 | 22.3
| HCB | 57.8 | 32.6 | 9.6
| JPT | 51.8 | 44.6 | 3.6
| YRI | 11.0 | 50.7 | 38.4
| ASW | 24.6 | 54.4 | 21.1
| CHB | 57.8 | 32.6 | 9.6
| CHD | 56.0 | 36.7 | 7.3
| GIH | 17.8 | 59.4 | 22.8
| LWK | 15.5 | 56.4 | 28.2
| MEX | 25.9 | 53.4 | 20.7
| MKK | 12.2 | 44.9 | 42.9
| TSI | 30.7 | 47.5 | 21.8
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19884611
|Title=Association of the glutamate transporter gene SLC1A1 with atypical antipsychotics-induced obsessive-compulsive symptoms
}}

{{PharmGKB
|RSID=rs3780412
|Name_s=SLC1A1:rs3780412A>G, SNP4, Intron 7
|Gene_s=SLC1A1
|Feature=
|Evidence=PubMed ID:19884611
|Annotation=Risk or phenotype-associated variant: G. Phenotype: The A/C/G haplotype at rs2228622-rs3780413-rs3780412 showed a significant association with atypical antipsychotic-induced obsessive compulsive symptoms. Study size: 94. Study population/ethnicity: Patients with schizophrenia receiving atypical antipsychotics; Asian; Korea. Significance metric(s): p = 0.04. Type of association: CO.
|Drugs=clozapine; olanzapine; risperidone
|Drug Classes=
|Diseases=Obsessive-Compulsive Disorder; Schizophrenia
|Curation Level=Curated
|PharmGKB Accession ID=PA165110323
}}

{{PMID|16818867}} Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder.

{{PMID|17894418}} Association of the SLC1A1 glutamate transporter gene and obsessive-compulsive disorder.

{{PMID|19349310|OA=1
}} A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder.

{{PMID|19360657|OA=1
}} Family-Based Association Testing of OCD-associated SNPs of SLC1A1 in an autism sample.

{{PMID|22531293}} Polymorphisms in the glutamate transporter gene SLC1A1 and obsessive-compulsive symptoms induced by second-generation antipsychotic agents.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3780412
|overall_frequency_n=67
|overall_frequency_d=128
|overall_frequency=0.523438
|n_genomes=39
|n_genomes_annotated=0
|n_haplomes=53
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}