{{Rsnum
|rsid=3804100
|Gene=TLR2
|Chromosome=4
|position=153704257
|Orientation=plus
|ReferenceAllele=T
|GMAF=0.1157
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=TLR2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.0 | 14.3 | 85.7
| HCB | 5.1 | 52.6 | 42.3
| JPT | 1.8 | 45.0 | 53.2
| YRI | 0.0 | 10.9 | 89.1
| ASW | 0.0 | 12.3 | 87.7
| CHB | 5.1 | 52.6 | 42.3
| CHD | 11.1 | 36.1 | 52.8
| GIH | 1.0 | 23.8 | 75.2
| LWK | 0.0 | 12.8 | 87.2
| MEX | 0.0 | 15.8 | 84.2
| MKK | 0.6 | 4.5 | 94.9
| TSI | 1.0 | 13.9 | 85.1
| HapMapRevision=28
}}[[rs3804100]], also known as 1350T/C, is a SNP in the toll-like receptor 2 [[TLR2]] gene.

A study of 700 T1D children, 357 nuclear families with T1D children and 796 children from the 'Environment and Childhood Asthma' study concluded that both [[type-1 diabetes]] and allergic [[asthma]] were significantly associated with the [[rs3804100]](T) allele.{{PMID|19148143}}

{{PMID Auto
|PMID=22235236
|Title=Toll-like receptor 2 gene polymorphisms associated with aggressive periodontitis in Japanese
|OA=1
}}

{{PMID Auto
|PMID=22309608
|Title=The association between Toll-like receptor 2 single-nucleotide polymorphisms and hepatocellular carcinoma susceptibility
|OA=1
}}

{{PMID Auto
|PMID=18325643
|Title=Associations between SNPs in toll-like receptors and related intracellular signaling molecules and immune responses to measles vaccine: preliminary results.
|OA=1
}}

{{PMID Auto
|PMID=18396467
|Title=Genetic variation and haplotype structures of innate immunity genes in eastern India.
|OA=1
}}

{{PMID Auto
|PMID=18556337
|Title=Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).
|OA=1
}}

{{PMID Auto
|PMID=19029192
|Title=A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma.
|OA=1
}}

{{PMID Auto
|PMID=19505919
|Title=Toll-like receptor signaling pathway variants and prostate cancer mortality.
|OA=1
}}

{{PMID Auto
|PMID=19543401
|Title=Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.
|OA=1
}}

{{PMID Auto
|PMID=20057905
|Title=Association of toll-like receptor 2 gene polymorphisms with normal tension glaucoma.
|OA=1
}}

{{PMID Auto
|PMID=20113509
|Title=Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts.
|OA=1
}}

{{PMID Auto
|PMID=20463618
|Title=Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.
|OA=1
}}

{{PMID Auto
|PMID=21111021
|Title=Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine.
}}

{{PMID Auto
|PMID=21424379
|Title=The role of polymorphisms in Toll-like receptors and their associated intracellular signaling genes in measles vaccine immunity.
|OA=1
}}

{{PMID Auto
|PMID=21437199
|Title=Toll-like receptor 2 (TLR2) gene polymorphisms are not associated with sarcoidosis in the Japanese population.
|OA=1
}}

{{PMID Auto
|PMID=21872627
|Title=Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.
}}

{{PMID Auto
|PMID=21887520
|Title=Association of toll-like receptor 2 polymorphisms with National Institute of Health Stroke Scale scores of ischemic stroke patients.
}}

{{PMID Auto
|PMID=23484049
|Title=Genetic Polymorphisms in Toll-Like Receptors among Pediatric Patients with Renal Parenchymal Infections of Different Clinical Severities
|OA=1
}}

{{PMID Auto
|PMID=23166414
|Title=Association of Toll-like receptor 2 polymorphisms with papillary thyroid cancer and clinicopathologic features in a Korean population
|OA=1
}}

{{PMID Auto
|PMID=23906542
|Title=Polymorphisms in TLR-2 are associated with congenital cytomegalovirus (CMV) infection but not with congenital CMV disease
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}