{{Rsnum
|rsid=3807306
|Gene=IRF5
|Chromosome=7
|position=128940626
|Orientation=minus
|GMAF=0.3494
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=IRF5
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 23.2 | 52.7 | 24.1
| HCB | 2.2 | 33.3 | 64.4
| JPT | 8.0 | 32.1 | 59.8
| YRI | 8.8 | 42.9 | 48.3
| ASW | 3.6 | 50.0 | 46.4
| CHB | 2.2 | 33.3 | 64.4
| CHD | 0.0 | 27.4 | 72.6
| GIH | 23.8 | 38.6 | 37.6
| LWK | 8.3 | 41.7 | 50.0
| MEX | 17.5 | 47.4 | 35.1
| MKK | 5.8 | 50.0 | 44.2
| TSI | 28.7 | 51.5 | 19.8
| HapMapRevision=28
}}{{PMID|18285424|OA=1
}} [[rs4728142]], [[rs3807306]] and a 5 bp insertion-deletion linked [[multiple sclerosis]] in three populations

{{PMID|18288123}} Associated with systemic lupus erythematosus ([[SLE]]) in African Americans.

{{omim
|desc=RHEUMATOID ARTHRITIS; RA
|id=180300
|rsnum=3807306
}}

{{omim
|desc=INTERFERON REGULATORY FACTOR 5; IRF5
|id=607218
|rsnum=3807306
}}

{{PMID Auto
|PMID=15657875
|Title=Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
|OA=1
}}

{{PMID Auto
|PMID=17189288
|Title=Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation.
|OA=1
}}

{{PMID Auto
|PMID=18668568
|Title=Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients.
|OA=1
}}

{{PMID Auto
|PMID=19109131
|Title=Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo.
|OA=1
}}

{{PMID Auto
|PMID=19956648
|Title=Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.
|OA=1
}}

{{PMID Auto
|PMID=20479942
|Title=Genetic risk factors in lupus nephritis and IgA nephropathy--no support of an overlap.
|OA=1
}}

{{PMID Auto
|PMID=20603721
|Title=Genome-wide association filtering using a highly locus-specific transmission/disequilibrium test.
|OA=1
}}

{{PMID Auto
|PMID=20861862
|Title=Validation of IRF5 as multiple sclerosis risk gene: putative role in interferon beta therapy and human herpes virus-6 infection.
}}

{{PMID Auto
|PMID=23971939
|Title=IRF5, but not TLR4, DEFEB1, or VDR, is associated with the risk of ulcerative colitis in a Han Chinese population
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}