{{Rsnum
|rsid=3807375
|Gene=KCNH2
|Chromosome=7
|position=150970122
|Orientation=minus
|GMAF=0.4219
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=KCNH2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 12.4 | 50.4 | 37.2
| HCB | 57.7 | 35.8 | 6.6
| JPT | 62.8 | 35.4 | 1.8
| YRI | 61.2 | 32.7 | 6.1
| ASW | 45.6 | 47.4 | 7.0
| CHB | 57.7 | 35.8 | 6.6
| CHD | 53.2 | 39.4 | 7.3
| GIH | 14.9 | 51.5 | 33.7
| LWK | 67.3 | 25.5 | 7.3
| MEX | 34.5 | 46.6 | 19.0
| MKK | 51.3 | 42.9 | 5.8
| TSI | 8.8 | 49.0 | 42.2
| HapMapRevision=28
}}{{PMID|19019189|OA=1
}} QT interval [[rs3807375]] [[rs2880058]]

{{PharmGKB
|RSID=rs3807375
|Name_s=
|Gene_s=KCNH2
|Feature=
|Evidence=PubMed ID:19019189
|Annotation=QT prolongation
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164856858
}}

{{PMID Auto GWAS
|PMID=20062063
|Trait=Electrocardiographic traits
|Title=Several common variants modulate heart rate, PR interval and QRS duration
|RiskAllele=T
|Pval=5E-11
|OR=11.95
|ORtxt=[8.39-15.51] % SD increase
}}

{{PMID Auto
|PMID=20215044
|Title=Relationship of Common Candidate Gene Variants to Electrocardiographic T-Wave Peak to T-Wave End Interval and T-Wave Morphology Parameters
|OA=1
}}

{{PharmGKB
|RSID=rs3807375
|Name_s=KCNH2:rs3807375
|Gene_s=KCNH2
|Feature=
|Evidence=PubMed ID:17709632
|Annotation=Associated with QT interval duration.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA161145090
}}

{{PMID Auto
|PMID=19214780
|Title=In silico investigations on functional and haplotype tag SNPs associated with congenital long QT syndromes (LQTSs).
|OA=1
}}

{{PMID Auto
|PMID=19305408
|Title=Common variants at ten loci influence QT interval duration in the QTGEN Study.
|OA=1
}}

{{PMID Auto
|PMID=19490382
|Title=Genetic polymorphism of KCNH2 confers predisposition of acquired atrial fibrillation in Chinese.
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3807375
|overall_frequency_n=67
|overall_frequency_d=126
|overall_frequency=0.531746
|n_genomes=42
|n_genomes_annotated=0
|n_haplomes=62
|n_articles=2
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}