{{Rsnum
|rsid=3810950
|Gene=CHAT
|Chromosome=10
|position=50824619
|Orientation=plus
|GMAF=0.1515
|Gene_s=CHAT
|Assembly=GRCh37.p5
|GenomeBuild=37.3
|dbSNPBuild=135
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 6.2 | 33.6 | 60.2
| HCB | 2.9 | 22.8 | 74.3
| JPT | 7.1 | 36.3 | 56.6
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 3.5 | 96.5
| CHB | 2.9 | 22.8 | 74.3
| CHD | 0.0 | 29.4 | 70.6
| GIH | 11.9 | 42.6 | 45.5
| LWK | 0.0 | 1.8 | 98.2
| MEX | 6.9 | 29.3 | 63.8
| MKK | 0.0 | 7.1 | 92.9
| TSI | 6.9 | 43.1 | 50.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=21507424
|Title=Genetic variation in the choline O-acetyltransferase gene in depression and Alzheimer's disease: the VITA and Milano studies
}}

{{PMID Auto
|PMID=21883924
|Title=Genetic variants in the choline acetyltransferase (ChAT) gene are modestly associated with normal cognitive function in the elderly.
|OA=1
}}

{{PMID|15690550}} Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study.

{{PMID|16223550|OA=1
}} Genetic variation in the choline acetyltransferase (CHAT) gene may be associated with the risk of Alzheimer's disease.

{{PMID|16480703}} ApoE-epsilon 4-dependent association of the choline acetyltransferase gene polymorphisms (2384G>A and 1882G>A) with Alzheimer's disease.

{{PMID|17503482}} Choline acetyltransferase variants and their influence in schizophrenia and olanzapine response.

{{PMID|18072279|OA=1
}} Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA.

{{PMID|20383528}} Replication and extension of association of choline acetyltransferase with nicotine dependence in European and African American smokers.

{{GET Evidence
|gene=CHAT
|aa_change=Ala120Thr
|aa_change_short=A120T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3810950
|overall_frequency_n=1983
|overall_frequency_d=10758
|overall_frequency=0.184328
|n_genomes=19
|n_genomes_annotated=0
|n_haplomes=21
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|pph2_score=0.013
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=1
|autoscore=3
|n_web_uneval=10
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}