{{Rsnum
|rsid=3814219
|Gene=OBFC1
|Chromosome=10
|position=105647095
|Orientation=plus
|GMAF=0.2094
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 8.8 | 40.7 | 50.4
| HCB | 1.5 | 23.4 | 75.2
| JPT | 0.9 | 31.0 | 68.1
| YRI | 3.4 | 25.2 | 71.4
| ASW | 5.3 | 28.1 | 66.7
| CHB | 1.5 | 23.4 | 75.2
| CHD | 2.8 | 33.9 | 63.3
| GIH | 1.0 | 19.8 | 79.2
| LWK | 3.6 | 38.2 | 58.2
| MEX | 1.7 | 31.0 | 67.2
| MKK | 3.8 | 25.0 | 71.2
| TSI | 5.9 | 42.2 | 52.0
| HapMapRevision=28
}}{{PMID|17903301|OA=1
}} BA baseline flow, [[rs3814219]] (OBFC1, 9.48*10(-7))

{{GWAS Summary
|SNP=rs3814219
|PubMedID=17903301
|Condition=Endothelial function traits
|Gene=OBFC1
|Risk Allele=
|pValue=9.00E-007
|OR=NA
|95CI=
|OA=1
}}

{{PharmGKB
|RSID=rs3814219
|Name_s=
|Gene_s=OBFC1
|Feature=
|Evidence=PubMed ID:17903301; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study (Initial Sample Size: 1,238 individuals (Framingham); Replication Sample Size: NR). This variant is associated with Endothelial function traits.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356469
}}

{{PMID Auto
|PMID=20369022
|Title=Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.
|OA=1
}}

{{PMID Auto
|PMID=20421499
|Title=Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3814219
|overall_frequency_n=26
|overall_frequency_d=128
|overall_frequency=0.203125
|n_genomes=19
|n_genomes_annotated=0
|n_haplomes=21
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}