{{Rsnum
|rsid=3815459
|Gene=KCNH2
|Chromosome=7
|position=150947306
|Orientation=minus
|GMAF=0.4073
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=KCNH2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 0.0 | 0.0
| HCB | 51.1 | 42.2 | 6.7
| JPT | 68.2 | 25.0 | 6.8
| YRI | 11.1 | 49.2 | 39.7
| ASW | 0.0 | 0.0 | 0.0
| CHB | 51.1 | 42.2 | 6.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}[http://blog.23andme.com/2009/03/23/snpwatch-researchers-identify-genetic-variants-linked-to-heart-rhythm-and-possibly-sudden-cardiac-death/ 23andMe blog] Influences [[QT interval]]

{{PharmGKB
|RSID=rs3815459
|Name_s=KCNH2:rs3815459
|Gene_s=KCNH2
|Feature=Intron
|Evidence=PubMed ID:15746444; PubMed ID:17534376
|Annotation=Associated with the QT interval; the A allele is more common with long QT.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA161145089
}}

{{PMID Auto
|PMID=19305408
|Title=Common variants at ten loci influence QT interval duration in the QTGEN Study.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3815459
|overall_frequency_n=1812
|overall_frequency_d=9228
|overall_frequency=0.196359
|n_genomes=4
|n_genomes_annotated=0
|n_haplomes=6
|n_articles=0
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=22688145
|Title=Clinical response and side effects of metoclopramide: associations with clinical, demographic, and pharmacogenetic parameters
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}