{{Rsnum
|rsid=3822086
|Gene=SNCA
|Chromosome=4
|position=89743643
|Orientation=plus
|GMAF=0.3522
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=SNCA
}}{{PharmGKB
|RSID=rs3822086
|Name_s=
|Gene_s=SNCA
|Feature=
|Evidence=PubMed ID:19771175
|Annotation=This intronic SNP in the SNCA gene is associated with Multiple System Atrophy (MSA) in the NNIPPS samples (Caucasian population); rs3822086 (P = 0.0044); multiple testing correction for association with MSA (P = 0.047). The repeated analysis in the MSA-C subgroup for this SNP found the association strengthened despite more than halving the number of cases: rs3822086 P = 0.0024.
|Drugs=
|Drug Classes=
|Diseases=Multiple System Atrophy
|Curation Level=Curated
|PharmGKB Accession ID=PA165107183
}}

{{PMID Auto
|PMID=15637659
|Title=Linkage disequilibrium patterns and tagSNP transferability among European populations.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3822086
|overall_frequency_n=48
|overall_frequency_d=128
|overall_frequency=0.375
|n_genomes=31
|n_genomes_annotated=0
|n_haplomes=44
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}