{{Rsnum
|rsid=3825776
|Gene=LIPC
|Chromosome=15
|position=58454631
|Orientation=minus
|GMAF=0.4169
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=LIPC,RP11-355N15.1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 39.8 | 51.3 | 8.8
| HCB | 29.9 | 49.6 | 20.4
| JPT | 17.7 | 60.2 | 22.1
| YRI | 25.9 | 58.5 | 15.6
| ASW | 40.4 | 45.6 | 14.0
| CHB | 29.9 | 49.6 | 20.4
| CHD | 19.3 | 52.3 | 28.4
| GIH | 42.6 | 42.6 | 14.9
| LWK | 25.5 | 50.9 | 23.6
| MEX | 17.2 | 46.6 | 36.2
| MKK | 20.5 | 48.7 | 30.8
| TSI | 46.1 | 42.2 | 11.8
| HapMapRevision=28
}}[[rs3825776]], a SNP in the region of the [[LIPC]] gene on chromosome 15, has been associated with the sporadic form of [[ALS]] (Lou Gehrig's disease) in a study of 1000+ European patients. The odds ratio for the risk allele [[rs3825776(G)]] is 1.34 (CI: 1.12 - 1.46). {{PMID|18084291}}

{{PMID Auto
|PMID=18078817
|Title=Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3825776
|overall_frequency_n=52
|overall_frequency_d=128
|overall_frequency=0.40625
|n_genomes=38
|n_genomes_annotated=0
|n_haplomes=45
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}