{{Rsnum
|rsid=3826656
|Gene=CD33
|Chromosome=19
|position=51223357
|Orientation=plus
|GMAF=0.3361
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CD33
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 67.3 | 26.5 | 6.2
| HCB | 10.2 | 39.4 | 50.4
| JPT | 3.5 | 32.7 | 63.7
| YRI | 68.7 | 27.2 | 4.1
| ASW | 59.6 | 33.3 | 7.0
| CHB | 10.2 | 39.4 | 50.4
| CHD | 8.3 | 40.7 | 50.9
| GIH | 21.8 | 50.5 | 27.7
| LWK | 70.9 | 28.2 | 0.9
| MEX | 60.3 | 32.8 | 6.9
| MKK | 51.9 | 41.0 | 7.1
| TSI | 58.8 | 34.3 | 6.9
| HapMapRevision=28
}}[http://www.genomeweb.com/issues/news/150344-1.html genomeweb] [[rs4420638]] [[rs11159647]] and [[rs3826656]] were also significantly associated with [[Alzheimer's disease]]

{{PMID Auto GWAS
|PMID=18976728
|Trait=Alzheimer's disease
|Title=Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE
|RiskAllele=
|Pval=0.000006
|OR=NR
|ORtxt=NR
|OA=1
}}

{{PharmGKB
|RSID=rs3826656
|Name_s=
|Gene_s=CD33
|Feature=
|Evidence=PubMed ID:18976728; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE. (Initial Sample Size: 941 affected individuals, 404 unaffected individuals; Replication Sample Size: 1,767 affected individuals, 838 unaffected individuals); (Region: 19q13.33; Reported Gene(s): CD33; Risk Allele: rs3826656-?); (p-value= 0.000006).This variant is associated with Alzheimer's disease.
|Drugs=
|Drug Classes=
|Diseases=Alzheimer Disease
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740769
}}

{{PharmGKB
|RSID=rs3826656
|Name_s=
|Gene_s=CD33
|Feature=
|Evidence=PubMed ID:18976728
|Annotation=In a GWAS of Alzheimer Disease families of self-reported European ancestry, this SNP was found to be associated with Alzheimer Disease. This association was also significant in replication attempts with three other family samples.
|Drugs=
|Drug Classes=
|Diseases=Alzheimer Disease
|Curation Level=Curated
|PharmGKB Accession ID=PA162356266
}}

{{PMID Auto
|PMID=20574532
|Title=Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
|OA=1
}}

{{PMID Auto
|PMID=22167654
|Title=Association studies of 19 candidate SNPs with sporadic Alzheimer's disease in the North Chinese Han population.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3826656
|overall_frequency_n=92
|overall_frequency_d=128
|overall_frequency=0.71875
|n_genomes=48
|n_genomes_annotated=0
|n_haplomes=77
|n_articles=2
|n_articles_annotated=2
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}