{{Rsnum
|rsid=3894194
|Gene=GSDMA
|Chromosome=17
|position=39965740
|Orientation=minus
|GMAF=0.4261
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=GSDMA
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 26.5 | 49.6 | 23.9
| HCB | 27.0 | 49.6 | 23.4
| JPT | 28.3 | 45.1 | 26.5
| YRI | 53.1 | 38.8 | 8.2
| ASW | 57.9 | 31.6 | 10.5
| CHB | 27.0 | 49.6 | 23.4
| CHD | 22.9 | 45.0 | 32.1
| GIH | 24.8 | 51.5 | 23.8
| LWK | 55.5 | 41.8 | 2.7
| MEX | 27.6 | 37.9 | 34.5
| MKK | 50.6 | 42.9 | 6.4
| TSI | 35.3 | 51.0 | 13.7
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20860503
|Trait=None
|Title=A large-scale, consortium-based genomewide association study of asthma
|RiskAllele=A
|Pval=5E-9
|OR=1.17
|ORtxt=[1.11-1.23]
}}

{{PMID Auto
|PMID=19426955
|Title=Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.
|OA=1
}}

{{PMID Auto
|PMID=22626592
|Title=17q12-21 variants are associated with asthma and interact with active smoking in an adult population from the United Kingdom.
}}

{{GET Evidence
|gene=GSDMA
|aa_change=Arg18Gln
|aa_change_short=R18Q
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3894194
|overall_frequency_n=4017
|overall_frequency_d=10016
|overall_frequency=0.401058
|n_genomes=37
|n_genomes_annotated=0
|n_haplomes=47
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.02
|nblosum100=0
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23028483
|Title=Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.
|OA=1
}}

{{PMID Auto GWAS
  |PMID=24241537
  |Trait=Asthma (childhood, severe)
  |Title=A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.
  |RiskAllele=A
  |Pval=3E-21
  |OR=1.59
  |ORtxt=[1.44-1.76]
  }}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}