{{Rsnum
|rsid=3905000
|Gene=ABCA1
|Chromosome=9
|position=104894789
|Orientation=plus
|GMAF=0.1327
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=ABCA1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 1.8 | 13.3 | 85.0
| HCB | 0.0 | 13.1 | 86.9
| JPT | 0.0 | 8.8 | 91.2
| YRI | 3.4 | 36.7 | 59.9
| ASW | 0.0 | 29.8 | 70.2
| CHB | 0.0 | 13.1 | 86.9
| CHD | 0.9 | 14.7 | 84.4
| GIH | 0.0 | 15.8 | 84.2
| LWK | 7.3 | 46.4 | 46.4
| MEX | 1.7 | 17.2 | 81.0
| MKK | 16.0 | 42.9 | 41.0
| TSI | 2.9 | 21.6 | 75.5
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19060911
|Trait=HDL cholesterol
|Title=Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
|RiskAllele=G
|Pval=9E-13
|OR=0.11
|ORtxt=[NR] SD increase
|OA=1
}}

{{PharmGKB
|RSID=rs3905000
|Name_s=
|Gene_s=ABCA1
|Feature=
|Evidence=PubMed ID:19060911; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (Initial Sample Size: 21,412 individuals; Replication Sample Size: NR); (Region: 9q31.1; Reported Gene(s): ABCA1; Risk Allele: rs3905000-G); (p-value= 0.0000000000009).This variant is associated with HDL cholesterol.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740206
}}

{{PMID Auto GWAS
|PMID=21116278
|Trait=None
|Title=Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease
|RiskAllele=
|Pval=0.000009
|OR=0.0126
|ORtxt=[NR] unit increase (interaction)
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{PMID Auto
|PMID=19951432
|Title=Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
|OA=1
}}

{{PMID Auto
|PMID=20502693
|Title=Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.
|OA=1
}}

{{PMID Auto
|PMID=21347282
|Title=Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3905000
|overall_frequency_n=22
|overall_frequency_d=128
|overall_frequency=0.171875
|n_genomes=13
|n_genomes_annotated=0
|n_haplomes=16
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}