{{Rsnum
|rsid=3909184
|Gene=FLOT1
|Chromosome=6
|position=30731607
|Orientation=minus
|GMAF=0.06107
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=FLOT1
}}Helps to identify [[HLA-B*1502]]

{{PharmGKB
|RSID=rs3909184
|Name_s=
|Gene_s=FLOT1
|Feature=
|Evidence=PubMed ID:16998491
|Annotation=Risk or phenotype-associated allele: allele 2. Phenotype: Combined alleles of rs3909184 (2) and rs2844682 (4) are tagging SNPs for HLA-B*1502 (0.011 allele frequency). Study size: 45. Study population/ethnicity: Unrelated Han Chinese from Beijing, China. Significance metric(s): Type of association: GN
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA165291970
}}

{{PharmGKB
|RSID=rs3909184
|Name_s=tagging SNP for HLA-B*1502
|Gene_s=FLOT1
|Feature=
|Evidence=PubMed ID:15057820; PubMed ID:16415921; PubMed ID:16538176; PubMed ID:16998491; PubMed ID:18370849; PubMed ID:18637831; Web Resource:http://www.fda.gov/cder/drug/InfoSheets/HCP/carbamazepineHCP.htm
|Annotation=This variant is a tagging SNP for HLA-B*1502, which is associated with severe adverse reactions of carbamazepine. Patients carrying the HLA-B*1502 allele have significant higher risk for severe skin reactions (Stevens Johnson syndrome and toxic epidermal necrolysis) associated with carbamazepine therapy.
|Drugs=carbamazepine; phenytoin
|Drug Classes=
|Diseases=Bipolar Disorder; Epidermal Necrolysis, Toxic; Epilepsy; Stevens-Johnson Syndrome
|Curation Level=Curated
|PharmGKB Accession ID=PA162168983
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3909184
|overall_frequency_n=6
|overall_frequency_d=128
|overall_frequency=0.046875
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=6
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}