{{Rsnum
|rsid=4072111
|Gene=IL16
|Chromosome=15
|position=81285798
|Orientation=minus
|ReferenceAllele=C
|MissenseAllele=T
|GMAF=0.1281
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=IL16
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 21.4 | 77.7
| HCB | 5.1 | 33.6 | 61.3
| JPT | 1.8 | 37.2 | 61.1
| YRI | 0.0 | 12.9 | 87.1
| ASW | 0.0 | 5.3 | 94.7
| CHB | 5.1 | 33.6 | 61.3
| CHD | 5.5 | 29.4 | 65.1
| GIH | 10.9 | 39.6 | 49.5
| LWK | 0.0 | 6.4 | 93.6
| MEX | 5.2 | 36.2 | 58.6
| MKK | 2.6 | 14.1 | 83.3
| TSI | 0.0 | 16.8 | 83.2
| HapMapRevision=28
}}{{PMID Auto
|PMID=19298795
|Title=The IL-16 gene polymorphisms and the risk of the systemic lupus erythematosus.
}}

{{PMID Auto
|PMID=22187702
|Title=Interleukin-16 (IL-16) gene polymorphisms in Iranian patients with colorectal cancer
}}

{{PMID Auto
|PMID=19073878
|Title=The association of interleukin-16 polymorphisms with IL-16 serum levels and risk of colorectal and gastric cancer.
}}

{{PMID Auto
|PMID=19758567
|Title=Genetic polymorphism of interleukin-16 and risk of nasopharyngeal carcinoma.
}}

{{GET Evidence
|gene=IL16
|aa_change=Pro434Ser
|aa_change_short=P434S
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4072111
|overall_frequency_n=876
|overall_frequency_d=10198
|overall_frequency=0.0858992
|n_genomes=15
|n_genomes_annotated=0
|n_haplomes=15
|n_articles=0
|n_articles_annotated=0
|nblosum100=3
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=24288444
|Title=Interleukin-16 Polymorphism Is Associated with an Increased Risk of Ischemic Stroke
|OA=1
}}

{{PMID Auto
|PMID=24175812
|Title=Variants of interleukin-16 associated with gastric cancer risk
}}

{{PMID Auto
|PMID=24969906
|Title=Positive Association Between IL-16 rs11556218 T/G Polymorphism and Cancer Risk: a Meta-analysis
}}

{{PMID Auto
|PMID=25166752
|Title=Interleukin-16 Polymorphism Is Associated with an Increased Risk of Glioma
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}