{{Rsnum
|rsid=4073
|Gene=CXCL8
|Chromosome=4
|position=73740307
|Orientation=plus
|GMAF=0.4972
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=CXCL8
}}{{PMID Auto
|PMID=19842025
|Title=Association of Interleukin-8 Gene Polymorphisms and Haplotypes with Oral Lichen Planus in a Chinese Population
}}

{{PMID Auto
|PMID=20431935
|Title=Polymorphisms in inflammatory genes, plasma antioxidants, and prostate cancer risk
|OA=1
}}
{{PMID Auto
|PMID=21042230
|Title=Genetic Polymorphisms and Susceptibility to Parenchymal Renal Infection Among Pediatric Patients
}}
{{PMID Auto
|PMID=21188496
|Title=Haplotypes in the Interleukin 8 Gene and Their Association with Chronic Periodontitis Susceptibility
}}

{{PMID Auto
|PMID=21637534
|Title=Interleukin-8-251T &gt; A, Interleukin-1?-889C &gt; T and Apolipoprotein E polymorphisms in Alzheimer's disease
|OA=1
}}

{{PMID Auto
|PMID=21649933
|Title=A promoter SNP rs4073T&gt;A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode
|OA=1
}}

{{PMID Auto
|PMID=21681427
|Title=-251 T/A polymorphism of the interleukin-8 gene and cancer risk: a HuGE review and meta-analysis based on 42 case-control studies
}}

{{PMID Auto
|PMID=21091348
|Title=Interleukin-8 gene promoter polymorphism (rs4073) may contribute to chronic periodontitis
|OA=1
}}

{{PMID Auto
|PMID=22132000
|Title=The IL1B-511 Polymorphism (rs16944 AA Genotype) Is Increased in Aspirin-Exacerbated Respiratory Disease in Mexican Population
|OA=1
}}

{{PMID Auto
|PMID=22727395
|Title=Genetic analysis of the IL8 gene polymorphism (rs4073) in generalized aggressive periodontitis
|OA=1
}}

{{PMID Auto
|PMID=22788685
|Title=Polymorphisms of pro-inflammatory cytokine genes and the risk for acute suppurative or chronic nonsuppurative apical periodontitis in a Colombian population
}}

{{PMID Auto
|PMID=16503988
|Title=Impact of IL8 and IL8-receptor alpha polymorphisms on the genetics of bronchial asthma and severe RSV infections.
|OA=1
}}

{{PMID Auto
|PMID=16719905
|Title=Association study of genetic variants of pro-inflammatory chemokine and cytokine genes in systemic lupus erythematosus.
|OA=1
}}

{{PMID Auto
|PMID=16820586
|Title=Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.
|OA=1
}}

{{PMID Auto
|PMID=17211588
|Title=Lack of association of IL8 gene polymorphisms with familial vesico-ureteral reflux.
}}

{{PMID Auto
|PMID=17327408
|Title=Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.
|OA=1
}}

{{PMID Auto
|PMID=17356794
|Title=Association of common polymorphisms in inflammatory genes with risk of developing cancers of the upper aerodigestive tract.
}}

{{PMID Auto
|PMID=17848170
|Title=The chemokine network. II. On how polymorphisms and alternative splicing increase the number of molecular species and configure intricate patterns of disease susceptibility.
|OA=1
}}

{{PMID Auto
|PMID=18549840
|Title=Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke.
|OA=1
}}

{{PMID Auto
|PMID=18633131
|Title=Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.
|OA=1
}}

{{PMID Auto
|PMID=18676870
|Title=Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.
|OA=1
}}

{{PMID Auto
|PMID=18992148
|Title=Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.
|OA=1
}}

{{PMID Auto
|PMID=19066394
|Title=Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.
|OA=1
}}

{{PMID Auto
|PMID=19347053
|Title=Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion.
|OA=1
}}

{{PMID Auto
|PMID=19356949
|Title=Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.
|OA=1
}}

{{PMID Auto
|PMID=19357773
|Title=Common variants of inflammatory cytokine genes are associated with risk of nephropathy in type 2 diabetes among Asian Indians.
|OA=1
}}

{{PMID Auto
|PMID=19364277
|Title=Lack of association of a functional polymorphism in the interleukin 8 gene with susceptibility to periodontitis.
}}

{{PMID Auto
|PMID=19390575
|Title=Lung cancer susceptibility model based on age, family history and genetic variants.
|OA=1
}}

{{PMID Auto
|PMID=19994728
|Title=Interleukin-8 T-251A polymorphism was associated with positive anti-p53 antibodies in Uzbekistan population.
}}

{{PMID Auto
|PMID=20015396
|Title=Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.
|OA=1
}}

{{PMID Auto
|PMID=20463618
|Title=Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.
|OA=1
}}

{{PMID Auto
|PMID=20811626
|Title=Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.
|OA=1
}}

{{PMID Auto
|PMID=21214373
|Title=Polymorphisms of CXCL8 and Its Receptor CXCR2 Contribute to the Development and Progression of Childhood IgA Nephropathy.
}}

{{PMID Auto
|PMID=22000099
|Title=Cytokine biomarkers and chronic pain: association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation tenderness.
|OA=1
}}

{{PMID Auto
|PMID=23545310
|Title=Association between -251A&gt;T polymorphism in the interleukin-8 gene and oral cancer risk: A meta-analysis
}}

{{PMID Auto
|PMID=23086128
|Title=Profiles of gene polymorphisms in cytokines and Toll-like receptors with higher risk for gastric cancer
}}

{{PMID Auto
|PMID=23831257
|Title=Association of IL-8 gene polymorphisms with Non Small Cell Lung Cancer in Tunisia: a case control study
}}

{{PMID Auto
|PMID=24072654
|Title=Influence of interleukin gene polymorphisms on development of acute pancreatitis: a systematic review and meta-analysis
}}

{{PMID Auto
|PMID=24462138
|Title=Association of interleukin 8 with myocardial infarction: Results from the Stockholm Heart Epidemiology Program
}}

{{PMID Auto
|PMID=23251429
|Title=Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study.
|OA=1
}}

{{PMID Auto
|PMID=25251027
|Title=Low IL-8 is associated with anxiety in suicidal patients: genetic variation and decreased protein levels
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}