{{Rsnum
|rsid=41298401
|Gene=IRF5
|Chromosome=7
|position=128938253
|Orientation=plus
|GMAF=0.08173
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=IRF5
}}{{PMID|18311811}}  Japanese 277 SLE patients and 201 controls. Carriers of the [[rs2004640]]T slightly increased among SLE patients (58.8%) as compared with controls (50.2%). When data from our Japanese population were combined with previously published data from a Korean population, the T allele frequency was found to be significantly increased in SLE patients (P = 8.3 x 10(-5)). While no association was observed for the [[rs10954213]] . significant associations with 3 intron 1 SNPs (-4001, [[rs6953165]], and [[rs41298401]]) were found. The allele frequency of [[rs41298401]]G was significantly decreased in SLE patients (13.0% versus 18.7% in controls; P = 0.017), and the allele frequency of [[rs6953165]]G, which was in absolute linkage disequilibrium with -4001A, was increased in SLE patients (8.8% versus 5.2% in controls; P = 0.034). The Caucasian risk haplotype was not present; instead, a protective haplotype carrying [[rs2004640]]G, [[rs41298401]]G, the deletion in exon 6, and [[rs10954213]]A was identified. SNP [[rs10954213]]
{{ neighbor
| rsid = 2004640
| distance = 6
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}