{{Rsnum
|rsid=4132601
|Gene=IKZF1
|Chromosome=7
|position=50402906
|Orientation=plus
|GMAF=0.2254
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=IKZF1
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 7.1 | 46.0 | 46.9
| HCB | 2.9 | 20.4 | 76.6
| JPT | 0.9 | 12.4 | 86.7
| YRI | 6.1 | 34.0 | 59.9
| ASW | 5.3 | 35.1 | 59.6
| CHB | 2.9 | 20.4 | 76.6
| CHD | 2.8 | 19.3 | 78.0
| GIH | 15.8 | 39.6 | 44.6
| LWK | 3.6 | 44.5 | 51.8
| MEX | 0.0 | 34.5 | 65.5
| MKK | 7.7 | 42.9 | 49.4
| TSI | 6.9 | 48.0 | 45.1
| HapMapRevision=28
}}[http://blog.23andme.com/2009/08/20/snpwatch-genetic-variants-associated-with-risk-of-childhood-acute-lymphoblastic-leukemia-identified/ 23andMe blog] [[Acute lymphoblastic leukemia]]
*each [[rs4132601]](G) 1.69x odds of ALL
*each [[rs7089424]](G) 1.65x odds of ALL
*each [[rs2239633]](G) 1.34x odds of ALL

{{PMID Auto GWAS
|PMID=19684604
|Trait=Acute lymphoblastic leukemia (childhood)
|Title=Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia
|RiskAllele=C
|Pval=1E-19
|OR=1.69
|ORtxt=[1.58-1.81]
}}

{{omim
|id=613067
|rsnum=4132601
}}

{{PMID Auto
|PMID=20919861
|Title=Variation at 7p12.2 and 10q21.2 influences childhood acute lymphoblastic leukemia risk in the Thai population and may contribute to racial differences in leukemia incidence.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4132601
|overall_frequency_n=29
|overall_frequency_d=128
|overall_frequency=0.226562
|n_genomes=17
|n_genomes_annotated=0
|n_haplomes=21
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=25012940
|Title=IKZF1 rs4132601 polymorphism and acute lymphoblastic leukemia susceptibility: a meta-analysis
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}