{{Rsnum
|rsid=4143832
|Chromosome=5
|position=132527285
|Orientation=minus
|GMAF=0.2002
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 1.8 | 30.1 | 68.1
| HCB | 0.7 | 26.3 | 73.0
| JPT | 0.0 | 36.3 | 63.7
| YRI | 21.1 | 51.0 | 27.9
| ASW | 7.0 | 36.8 | 56.1
| CHB | 0.7 | 26.3 | 73.0
| CHD | 0.0 | 25.0 | 75.0
| GIH | 2.0 | 26.7 | 71.3
| LWK | 5.5 | 43.1 | 51.4
| MEX | 0.0 | 22.4 | 77.6
| MKK | 5.8 | 37.2 | 57.1
| TSI | 2.9 | 26.5 | 70.6
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19198610
|Trait=Plasma eosinophil count
|Title=Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
|RiskAllele=C
|Pval=1E-10
|OR=7.10
|ORtxt=[4.9-9.2] % standard unit increase
}}

{{omim
|desc=INTERLEUKIN 5; IL5
|id=147850
|rsnum=4143832
}}

{{PharmGKB
|RSID=rs4143832
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19198610; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. (Initial Sample Size: 9,392 individuals; Replication Sample Size: 12,118 individuals); (Region: 5q31.1; Reported Gene(s): IL5; Risk Allele: rs4143832-C); (p-value= 0.0000000001).This variant is associated with Plasma eosinophil count.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739964
}}

{{PMID|18056382|OA=1
}} Analysis of the 5q31 33 locus shows an association between single nucleotide polymorphism variants in the IL-5 gene and symptomatic infection with the human blood fluke, Schistosoma japonicum.

{{PMID|18614543|OA=1
}} The 5q31 variants associated with psoriasis and Crohn's disease are distinct.

{{PMID|19860791}} Genetic evidence for a role of IL33 in nasal polyposis.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4143832
|overall_frequency_n=100
|overall_frequency_d=128
|overall_frequency=0.78125
|n_genomes=53
|n_genomes_annotated=0
|n_haplomes=87
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=23328882
|Title=Meta-analyses of four eosinophil related gene variants in coronary heart disease.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}