{{Rsnum
|rsid=4149268
|Gene=ABCA1
|Chromosome=9
|position=104884939
|Orientation=minus
|GMAF=0.421
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=ABCA1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 8.0 | 39.8 | 52.2
| HCB | 5.1 | 41.6 | 53.3
| JPT | 15.9 | 42.5 | 41.6
| YRI | 51.0 | 42.9 | 6.1
| ASW | 54.4 | 38.6 | 7.0
| CHB | 5.1 | 41.6 | 53.3
| CHD | 8.3 | 44.0 | 47.7
| GIH | 38.0 | 43.0 | 19.0
| LWK | 47.3 | 45.5 | 7.3
| MEX | 15.5 | 39.7 | 44.8
| MKK | 54.5 | 40.4 | 5.1
| TSI | 20.6 | 41.2 | 38.2
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=18193043
|Trait=HDL cholesterol
|Title=Newly identified loci that influence lipid concentrations and risk of coronary artery disease
|RiskAllele=C
|Pval=1E-10
|OR=0.82
|ORtxt=[NR] mg/dl higher
}}

G allele is associated with 0.82mg/dl increase in [[HDL cholesterol]] (good cholesterol). {{PMID|18193043}}

{{PMID Auto
|PMID=21738485
|Title=Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study
|OA=1
}}

{{PMID Auto
|PMID=18852197
|Title=Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
|OA=1
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{PMID Auto
|PMID=19060910
|Title=Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|OA=1
}}

{{PMID Auto
|PMID=19185284
|Title=Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.
|OA=1
}}

{{PMID Auto
|PMID=19435741
|Title=Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.
|OA=1
}}

{{PMID Auto
|PMID=19606474
|Title=A survey of ABCA1 sequence variation confirms association with dementia.
|OA=1
}}

{{PMID Auto
|PMID=19802338
|Title=Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4149268
|overall_frequency_n=71
|overall_frequency_d=128
|overall_frequency=0.554688
|n_genomes=43
|n_genomes_annotated=0
|n_haplomes=60
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}