{{Rsnum
|rsid=4151620
|Gene=RB1
|Chromosome=13
|position=48474923
|Orientation=plus
|GMAF=0.1001
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=RB1
}}[[rs4151620(C;G)]] and [[rs4151620(G;G)]] are associated with a reduced risk of [[ovarian cancer]] compared with [[rs4151620(G;G)]] individuals. 

This snp has been linked to [[ovarian cancer]] {{PMID|17047088}}

Intron 17 of RB1 contains the open reading frame for the [[P2RY5]] gene, and [[rs4151620]] is perfectly correlated with [[rs2227311]], which is located in the 5'-untranslated region of P2RY5 and is predicted to affect P2RY5 transcription. [[rs2854344]] has been reported previously to be associated with [[breast cancer]] risk {{PMID|16685266|OA=1
}}

{{PMID Auto
|PMID=18281541
|Title=Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.
|OA=1
}}

{{PMID Auto
|PMID=19258477
|Title=Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.
|OA=1
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}