{{Rsnum
|rsid=4151659
|Gene=CFB
|Chromosome=6
|position=31950687
|Orientation=plus
|GMAF=0.01837
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CFB
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 99.1 | 0.9 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 89.0 | 11.0 | 0.0
| ASW | 92.9 | 7.1 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 91.7 | 8.3 | 0.0
| MEX | 91.4 | 8.6 | 0.0
| MKK | 59.1 | 40.9 | 0.0
| TSI | 96.0 | 4.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20054343
|Title=Genetic variation within the HLA class III influences T1D susceptibility conferred by high-risk HLA haplotypes
|OA=1
}}

{{PMID Auto
|PMID=18806293
|Title=Analysis of rare variants in the complement component 2 (C2) and factor B (BF) genes refine association for age-related macular degeneration (AMD).
}}

{{PMID Auto
|PMID=19143814
|Title=Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1.
|OA=1
}}

{{PMID Auto
|PMID=19143815
|Title=MHC fine mapping of human type 1 diabetes using the T1DGC data.
|OA=1
}}

{{PMID Auto
|PMID=19259132
|Title=Multilocus analysis of age-related macular degeneration.
|OA=1
}}

{{GET Evidence
|gene=CFB
|aa_change=Lys565Glu
|aa_change_short=K565E
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4151659
|overall_frequency_n=3
|overall_frequency_d=128
|overall_frequency=0.0234375
|n_genomes=2
|n_genomes_annotated=0
|n_haplomes=2
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|pph2_score=0.03
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=0
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}