{{Rsnum
|rsid=422951
|Gene=NOTCH4
|Chromosome=6
|position=32220606
|Orientation=minus
|GMAF=0.3347
|Gene_s=NOTCH4
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 35.4 | 45.1 | 19.5
| HCB | 64.9 | 29.9 | 5.2
| JPT | 57.1 | 34.8 | 8.0
| YRI | 57.1 | 36.7 | 6.1
| ASW | 59.6 | 29.8 | 10.5
| CHB | 64.9 | 29.9 | 5.2
| CHD | 65.1 | 29.4 | 5.5
| GIH | 26.7 | 50.5 | 22.8
| LWK | 48.2 | 43.6 | 8.2
| MEX | 55.2 | 37.9 | 6.9
| MKK | 23.2 | 47.1 | 29.7
| TSI | 26.0 | 47.0 | 27.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=22732452
|Title=Investigation of NOTCH4 coding region polymorphisms in sporadic inclusion body myositis
}}

{{GET Evidence
|gene=NOTCH4
|aa_change=Thr320Ala
|aa_change_short=T320A
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs422951
|overall_frequency_n=2956
|overall_frequency_d=7524
|overall_frequency=0.392876
|n_genomes=33
|n_genomes_annotated=0
|n_haplomes=42
|n_articles=0
|n_articles_annotated=0
|nblosum100=1
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=15091315
|Title=Is NOTCH4 associated with schizophrenia?
}}

{{PMID Auto
|PMID=23549433
|Title=A NOTCH4 missense mutation confers resistance to multiple sclerosis in Japanese.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}