{{Rsnum
|rsid=4251417
|Gene=SLC6A4
|Chromosome=17
|position=30224840
|Orientation=minus
|GMAF=0.03857
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SLC6A4
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 2.7 | 16.8 | 80.5
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 1.8 | 98.2
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 1.0 | 99.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 6.9 | 93.1
| MKK | 0.0 | 0.0 | 0.0
| TSI | 2.0 | 11.8 | 86.3
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs4251417
|Name_s=
|Gene_s=SLC6A4
|Feature=
|Evidence=PubMed ID:19541292
|Annotation=This study identified a two-SNP haplotype proxy for 5HTTLPR (the length polymorphism repeat in the promoter region of the SLC6A4 gene) ; the CA haplotype of SNPs rs4251417 and rs2020934 is coupled with the short allele of 5HTTLPR (r(2) = .72).
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164920374
}}

{{PMID|15361494|OA=1
}} Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women.

{{PMID|18937309|OA=1
}} Sexually dimorphic effects of four genes (COMT, SLC6A2, MAOA, SLC6A4) in genetic associations of ADHD: a preliminary study.

{{PMID|19199283|OA=1
}} Variants of the serotonin transporter gene and NEO-PI-R Neuroticism: No association in the BLSA and SardiNIA samples.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4251417
|overall_frequency_n=4
|overall_frequency_d=128
|overall_frequency=0.03125
|n_genomes=3
|n_genomes_annotated=0
|n_haplomes=4
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=2
|webscore=N
|n_web_uneval=10
}}

{{PMID Auto
|PMID=22947179
|Title=Analysis of 34 candidate genes in bupropion and placebo remission
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}