{{Rsnum
|rsid=4251961
|Gene=IL1RN
|Chromosome=2
|position=113116890
|Orientation=plus
|GMAF=0.23
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=IL1RN
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 12.4 | 52.2 | 35.4
| HCB | 2.2 | 19.0 | 78.8
| JPT | 0.0 | 13.3 | 86.7
| YRI | 1.4 | 18.4 | 80.3
| ASW | 3.5 | 24.6 | 71.9
| CHB | 2.2 | 19.0 | 78.8
| CHD | 0.0 | 12.8 | 87.2
| GIH | 12.9 | 39.6 | 47.5
| LWK | 0.9 | 22.7 | 76.4
| MEX | 8.6 | 48.3 | 43.1
| MKK | 5.8 | 39.7 | 54.5
| TSI | 10.8 | 52.0 | 37.3
| HapMapRevision=28
}}{{PMID Auto
|PMID=21248262
|Title=The IL1RN Promoter rs4251961 Correlates with IL-1 Receptor Antagonist Concentrations in Human Infection and Is Differentially Regulated by GATA-1
}}

{{PMID Auto
|PMID=21968104
|Title=The association of genetic variants in interleukin-1 genes with cognition: findings from the cardiovascular health study
|OA=1
}}

{{PMID Auto
|PMID=17443229
|Title=Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels.
}}

{{PMID Auto
|PMID=18451331
|Title=Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation.
|OA=1
}}

{{PMID Auto
|PMID=18635889
|Title=Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.
|OA=1
}}

{{PMID Auto
|PMID=18853133
|Title=Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=19104506
|Title=Variations in the interleukin-1 receptor antagonist gene impact on survival of patients with advanced colorectal cancer.
}}

{{PMID Auto
|PMID=19347053
|Title=Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion.
|OA=1
}}

{{PMID Auto
|PMID=19729864
|Title=Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study.
|OA=1
}}

{{PMID Auto
|PMID=19934104
|Title=Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations.
|OA=1
}}

{{PMID Auto
|PMID=20031576
|Title=Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.
|OA=1
}}

{{PMID Auto
|PMID=20031590
|Title=The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations.
|OA=1
}}

{{PMID Auto
|PMID=22205395
|Title=Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African Americans.
|OA=1
}}

{{PMID Auto
|PMID=24233813
|Title=Stroke, IL-1ra, IL1RN, Infection and Outcome
}}

{{PMID Auto
|PMID=23602982
|Title=IL-1 receptor antagonist gene as a predictive biomarker of progression of knee osteoarthritis in a population cohort
}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}