{{Rsnum
|rsid=4252596
|Gene=ERBB2
|Chromosome=17
|position=39699581
|Orientation=plus
|GMAF=0.05096
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=ERBB2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 0.9 | 26.1 | 73.0
| HCB | 0.0 | 0.7 | 99.3
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 0.0
| ASW | 0.0 | 3.6 | 96.4
| CHB | 0.0 | 0.7 | 99.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 2.0 | 30.0 | 68.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 1.8 | 98.2
| MKK | 0.0 | 0.0 | 0.0
| TSI | 2.0 | 25.7 | 72.3
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs4252596
|Name_s=
|Gene_s=ERBB2
|Feature=
|Evidence=PubMed ID:15743501
|Annotation=Risk or phenotype-associated allele: none. Phenotype: Breast cancer risk. Study size: 2192 (1438 incident and 754 prevalent) cases and 2257 controls. Study population/ethnicity: British female breast cancer patients < 55 years of age (prevalent cases) recruited between 1 January 1991 and 30 June 1996, and < 70 years of age diagnosed from 1996 onwards (incident cases), and ethinic-matched European controls. Significance metric(s): p = 0.13 (non-significant). Type of association: GN; CO.
|Drugs=
|Drug Classes=
|Diseases=Breast Neoplasms
|Curation Level=Curated
|PharmGKB Accession ID=PA165290956
}}

{{PMID Auto
|PMID=17132159
|Title=Comprehensive analysis of the ATM, CHEK2 and ERBB2 genes in relation to breast tumour characteristics and survival: a population-based case-control and follow-up study.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4252596
|overall_frequency_n=13
|overall_frequency_d=128
|overall_frequency=0.101562
|n_genomes=9
|n_genomes_annotated=0
|n_haplomes=9
|n_articles=1
|n_articles_annotated=1
|in_pharmgkb=Y
|autoscore=2
|webscore=N
|n_web_uneval=10
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}