{{Rsnum
|rsid=4293
|Gene=ACE
|Chromosome=17
|position=63478305
|Orientation=plus
|GMAF=0.4867
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=ACE
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 34.5 | 46.0 | 19.5
| HCB | 48.9 | 40.1 | 10.9
| JPT | 29.2 | 51.3 | 19.5
| YRI | 0.7 | 17.0 | 82.3
| ASW | 3.5 | 33.3 | 63.2
| CHB | 48.9 | 40.1 | 10.9
| CHD | 33.0 | 54.1 | 12.8
| GIH | 27.7 | 54.5 | 17.8
| LWK | 1.8 | 21.8 | 76.4
| MEX | 46.6 | 39.7 | 13.8
| MKK | 2.6 | 33.3 | 64.1
| TSI | 26.5 | 46.1 | 27.5
| HapMapRevision=28
}}{{PMID Auto
|PMID=20854388
|Title=Investigation of ACE, ACE2 and AGTR1 genes for association with nephropathy in [[Type 1 diabetes]] mellitus
}}

This SNP in the antiotensin I converting enzyme ([[ACE]]) gene may  be associated with a higher risk of [[Alzheimer's disease]]. The risk allele is reported as A in a table published by the [[http://www.alzgene.org/geneoverview.asp?geneid=125 Alzheimer Research Forum]].

{{PMID Auto
|PMID=21261619
|Title=Genetic variation in renin predicts the effects of thiazide diuretics
}}

{{PMID Auto
|PMID=20463618
|Title=Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}