{{Rsnum
|rsid=4293393
|Gene=UMOD
|Chromosome=16
|position=20353266
|Orientation=minus
|GMAF=0.1685
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=UMOD
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 2.7 | 30.1 | 67.3
| HCB | 0.7 | 20.4 | 78.8
| JPT | 0.0 | 8.8 | 91.2
| YRI | 4.8 | 32.7 | 62.6
| ASW | 1.8 | 42.1 | 56.1
| CHB | 0.7 | 20.4 | 78.8
| CHD | 0.0 | 10.1 | 89.9
| GIH | 7.0 | 35.0 | 58.0
| LWK | 0.9 | 42.7 | 56.4
| MEX | 1.7 | 36.2 | 62.1
| MKK | 9.0 | 41.7 | 49.4
| TSI | 2.9 | 26.5 | 70.6
| HapMapRevision=28
}}
[http://blog.23andme.com/2009/05/13/snpwatch-variation-in-urine-protein-gene-may-decrease-risk-of-chronic-kidney-disease/ 23andMe blog] each G at rs4293393 decreased the odds of [[chronic kidney disease]] by 24%.  Approximately 18% of people with European ancestry have at least one G at this SNP.

DeCode reports that the T allele of [[rs4293393]] is associated with [[kidney stones]] and [[chronic kidney disease]]. [http://decodeyou.com/chronic-kidney-disease-added-to-decodeme/] This SNP may also be associated with susceptibility to [[gout]], [[hypertension]], and [[diabetes]]. {{PMID|20686651|OA=1
}} 

{{PMID Auto
|PMID=19959715
|Title=Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD
|OA=1
}}

{{PMID Auto
|PMID=20686651
|Title=Association of Variants at UMOD with Chronic Kidney Disease and Kidney Stones-Role of Age and Comorbid Diseases
|OA=1
}}

{{PMID Auto
|PMID=20222955
|Title=A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}