{{Rsnum
|rsid=4295627
|Chromosome=8
|position=129673211
|Orientation=plus
|GMAF=0.202
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 2.7 | 20.4 | 77.0
| HCB | 8.0 | 40.9 | 51.1
| JPT | 2.7 | 32.7 | 64.6
| YRI | 0.0 | 23.8 | 76.2
| ASW | 1.8 | 21.1 | 77.2
| CHB | 8.0 | 40.9 | 51.1
| CHD | 6.4 | 37.6 | 56.0
| GIH | 3.0 | 36.6 | 60.4
| LWK | 4.5 | 34.5 | 60.9
| MEX | 3.4 | 36.2 | 60.3
| MKK | 5.1 | 32.1 | 62.8
| TSI | 2.9 | 30.4 | 66.7
| HapMapRevision=28
}}
[http://blog.23andme.com/2009/07/06/snpwatch-genetic-variants-near-tumor-suppressor-genes-may-increase-risk-for-brain-and-skin-cancer/ 23andMe blog] [[rs4295627]] G 1.36 [[Glioma]]

{{PMID Auto GWAS
|PMID=19578367
|Trait=Glioma
|Title=Genome-wide association study identifies five susceptibility loci for glioma
|RiskAllele=G
|Pval=2E-18
|OR=1.36
|ORtxt=[1.29-1.43]
}}

{{PMID Auto
|PMID=20462933
|Title=Interaction between 5 genetic variants and allergy in glioma risk
}}
{{PMID Auto
|PMID=20847058
|Title=Genetic risk profiles identify different molecular etiologies for glioma
|OA=1
}}
{{PMID Auto
|PMID=20211558
|Title=Genetic advances in glioma: susceptibility genes and networks
|OA=1
}}

{{PMID Auto GWAS
|PMID=21531791
|Trait=None
|Title=Chromosome 7p11.2 (EGFR) variation influences glioma risk.
|RiskAllele=
|Pval=5E-21
|OR=1.4000
|ORtxt=[NR]
|OA=1
}}

{{PMID|20212223}} New insights into susceptibility to glioma.

{{PMID|21356187|OA=1
}} Distinct germ line polymorphisms underlie glioma morphologic heterogeneity.

{{PMID|21825990}} Genetic causes of glioma: new leads in the labyrinth.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4295627
|overall_frequency_n=23
|overall_frequency_d=128
|overall_frequency=0.179688
|n_genomes=17
|n_genomes_annotated=0
|n_haplomes=18
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23161787
|Title=Association between glioma susceptibility loci and tumour pathology defines specific molecular etiologies
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}