{{Rsnum
|rsid=4311
|Gene=ACE
|Chromosome=17
|position=63483402
|Orientation=plus
|GMAF=0.3503
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ACE
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 31.0 | 51.3 | 17.7
| HCB | 53.3 | 39.4 | 7.3
| JPT | 31.9 | 54.0 | 14.2
| YRI | 65.3 | 28.6 | 6.1
| ASW | 64.9 | 31.6 | 3.5
| CHB | 53.3 | 39.4 | 7.3
| CHD | 40.7 | 49.1 | 10.2
| GIH | 45.5 | 47.5 | 6.9
| LWK | 78.2 | 19.1 | 2.7
| MEX | 46.6 | 37.9 | 15.5
| MKK | 55.1 | 39.7 | 5.1
| TSI | 15.7 | 52.0 | 32.4
| HapMapRevision=28
}}
{{PMID|19108684}} A haplotype of [[rs4311]], [[rs4343]], [[rs699]] increases risk of [[diabetic nephropathy]] 4x.

{{PMID|17376814}} The risk allele T may be associated with about 1.2x increased risk of [[diabetic nephropathy]].

{{PMID Auto
|PMID=20381197
|Title=ACE variants and risk of intracerebral hemorrhage recurrence in amyloid angiopathy
}}

{{PMID Auto
|PMID=16222048
|Title=Effects of interaction between angiotensin I-converting enzyme polymorphisms and lifestyle on adiposity in adolescent Greeks.
}}

{{PMID Auto
|PMID=16391565
|Title=The associations of ACE polymorphisms with physical, physiological and skill parameters in adolescents.
}}

{{PMID Auto
|PMID=18076107
|Title=Confronting complexity in late-onset Alzheimer disease: application of two-stage analysis approach addressing heterogeneity and epistasis.
|OA=1
}}

{{PMID Auto
|PMID=19105203
|Title=An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.
|OA=1
}}

{{PMID Auto
|PMID=19963597
|Title=Visual exploration of genetic association with voxel-based imaging phenotypes in an MCI/AD study.
|OA=1
}}

{{PMID Auto
|PMID=20346360
|Title=Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.
|OA=1
}}

{{PMID Auto
|PMID=21709586
|Title=Common variants of the ACE gene and aneurysmal subarachnoid hemorrhage in a Danish population: a case-control study.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}