{{Rsnum
|rsid=4341
|Gene=ACE
|Chromosome=17
|position=63488629
|Orientation=plus
|GMAF=0.4826
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=ACE
}}{{PharmGKB
|RSID=rs4341
|Name_s=
|Gene_s=ACE
|Feature=
|Evidence=PubMed ID:19247266
|Annotation=Risk or phenotype-associated allele: GG. Phenotype:Increased risk of diabetes associated with thiazide use, this risk was more increased for ACE GG subjects Study size: 497 incident cases of type 2 diabetes and 2,633 controls. metric(s): SI 1.70 (95% CI: 1.08-2.66). Type of association: GN.
|Drugs=
|Drug Classes=THIAZIDE DERIVATIVES
|Diseases=Diabetes Mellitus, Type 2
|Curation Level=Curated
|PharmGKB Accession ID=PA165109227
}}

{{PMID Auto
|PMID=20402757
|Title=The I/D polymorphism of the ACE1 gene is not associated with ischaemic stroke in Spanish individuals
}}

{{PMID Auto
|PMID=12733698
|Title=An alternative fast and convenient genotyping method for the screening of angiotensin converting enzyme gene polymorphisms.
}}

{{PMID Auto
|PMID=18622756
|Title=An alternative method for genotyping of the ACE I/D polymorphism.
}}

{{PMID Auto
|PMID=19291311
|Title=ACE I/D genotype, adiposity, and blood pressure in children.
|OA=1
}}

{{PMID Auto
|PMID=20463618
|Title=Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4341
|overall_frequency_n=4724
|overall_frequency_d=10758
|overall_frequency=0.439115
|n_genomes=32
|n_genomes_annotated=0
|n_haplomes=39
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=24980618
|Title=Genotypes of the renin-angiotensin system and glucocorticoid complications
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}