{{Rsnum
|rsid=4359
|Gene=ACE
|Chromosome=17
|position=63494982
|Orientation=plus
|GMAF=0.4518
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ACE
}}This SNP in the [[ACE]] gene, also known as C17888T, is reported to influence how quickly African Americans respond to the anti-hypertensive drug [[ramipril]]. [[rs4359(C;C)]] and [[rs4359(T;T)]] homozygotes are able to reach lower blood pressure levels upon treatment with [[ramipril]] sooner than [[rs4359(C;T)]] heterozygotes. The odds ratio reported for this study, comparing both homozygotes to heterozygotes, is 1.49 (CI: 1.01-2.13). {{PMID|17885551|OA=1
}}

{{PMID Auto
|PMID=24918908
|Title=Genomic and Metabolomic Profile Associated to Microalbuminuria
}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}