{{Rsnum
|rsid = 4378650
|geno1 = (A;A)
|geno2 = (A;G)
|geno3 = (G;G)
|Gene = ORMDL3
|Orientation=plus
|Chromosome=17
|position=39924612
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Status=Merged
|Merged=4065275
|Gene_s=ORMDL3
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 20.4 | 54.9 | 24.8
| HCB | 10.9 | 49.6 | 39.4
| JPT | 8.8 | 40.7 | 50.4
| YRI | 6.8 | 37.4 | 55.8
| ASW | 24.6 | 36.8 | 38.6
| CHB | 10.9 | 49.6 | 39.4
| CHD | 6.4 | 41.3 | 52.3
| GIH | 16.8 | 44.6 | 38.6
| LWK | 17.3 | 52.7 | 30.0
| MEX | 17.2 | 46.6 | 36.2
| MKK | 42.9 | 41.7 | 15.4
| TSI | 23.5 | 52.0 | 24.5
| HapMapRevision=28
}}

{{PMID|18310477|OA=1
}} 264 African American [[asthma]] subjects and 176 healthy controls. (p = 0.028 and 0.001 for [[rs4378650]] and p = 0.021 and 0.001 for [[rs12603332]]), and a trend towards association in Puerto Ricans (p = 0.076 and 0.080 for SNPs [[rs4378650]] and rs12603332, respectively)

{{PMID Auto
|PMID=19133921
|Title=Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma
|OA=1
}}

{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}