{{Rsnum
|rsid=4379857
|Gene=OPCML
|Chromosome=11
|position=133313709
|Orientation=plus
|GMAF=0.1713
|Gene_s=OPCML,TBK1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 13.3 | 86.7
| HCB | 25.5 | 44.5 | 29.9
| JPT | 18.6 | 45.1 | 36.3
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 3.5 | 96.5
| CHB | 25.5 | 44.5 | 29.9
| CHD | 35.8 | 33.9 | 30.3
| GIH | 0.0 | 16.8 | 83.2
| LWK | 0.0 | 0.0 | 0.0
| MEX | 15.5 | 36.2 | 48.3
| MKK | 0.0 | 4.5 | 95.5
| TSI | 0.0 | 11.8 | 88.2
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs4379857
|Name_s=
|Gene_s=OPCML
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Smoking Initiation (p = 0.00009737; OR for minor allele A:0.645)
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164920605
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4379857
|overall_frequency_n=13
|overall_frequency_d=128
|overall_frequency=0.101562
|n_genomes=11
|n_genomes_annotated=0
|n_haplomes=12
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}