{{Rsnum
|rsid=4423615
|Gene=GRB14
|Chromosome=2
|position=164581720
|Orientation=plus
|GMAF=0.4454
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=GRB14
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 24.8 | 57.5 | 17.7
| HCB | 7.4 | 43.0 | 49.6
| JPT | 28.6 | 41.1 | 30.4
| YRI | 8.2 | 34.9 | 56.8
| ASW | 12.3 | 42.1 | 45.6
| CHB | 7.4 | 43.0 | 49.6
| CHD | 9.3 | 38.9 | 51.9
| GIH | 25.7 | 43.6 | 30.7
| LWK | 7.3 | 46.8 | 45.9
| MEX | 22.4 | 50.0 | 27.6
| MKK | 14.2 | 49.7 | 36.1
| TSI | 27.7 | 43.6 | 28.7
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs4423615
|Name_s=
|Gene_s=GRB14
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Smoking Initiation (p = 0.0000529; OR for minor allele G:0.815)
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164920582
}}

{{PharmGKB
|RSID=rs4423615
|Name_s=
|Gene_s=GRB14
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Current Smoking (p = 0.00006777;OR for minor allele G:0.811).
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164924500
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4423615
|overall_frequency_n=55
|overall_frequency_d=128
|overall_frequency=0.429688
|n_genomes=34
|n_genomes_annotated=0
|n_haplomes=42
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}