{{Rsnum
|rsid=4505848
|Gene=KIAA1109
|Chromosome=4
|position=122211337
|Orientation=plus
|GMAF=0.3356
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=KIAA1109
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 37.2 | 49.6 | 13.3
| HCB | 20.6 | 57.4 | 22.1
| JPT | 12.4 | 63.7 | 23.9
| YRI | 91.8 | 8.2 | 0.0
| ASW | 78.9 | 21.1 | 0.0
| CHB | 20.6 | 57.4 | 22.1
| CHD | 29.6 | 49.1 | 21.3
| GIH | 43.4 | 48.5 | 8.1
| LWK | 78.9 | 20.2 | 0.9
| MEX | 34.5 | 34.5 | 31.0
| MKK | 69.7 | 27.7 | 2.6
| TSI | 50.0 | 42.2 | 7.8
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19302705
|Title=Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study.
|OA=1
}}

{{PMID Auto GWAS
|PMID=19430480
|Trait=Type 1 diabetes
|Title=Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
|RiskAllele=
|Pval=5E-13
|OR=NR
|ORtxt=NR
|OA=1
}}

{{omim
|desc=CELIAC DISEASE, SUSCEPTIBILITY TO, 6; CELIAC6
|id=611598
|rsnum=4505848
}}

{{PMID Auto
|PMID=22065918
|Title=CFH 184G as a genetic risk marker for anterior uveitis in Chinese females
|OA=1
}}

{{PMID|17558408|OA=1
}} A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.

{{PMID|17999365|OA=1
}} Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases.

{{PMID|20553587|OA=1
}} Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs4505848
|overall_frequency_n=38
|overall_frequency_d=128
|overall_frequency=0.296875
|n_genomes=26
|n_genomes_annotated=0
|n_haplomes=32
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}