{{Rsnum
|rsid=4516035
|Gene=VDR
|Chromosome=12
|position=47906043
|Orientation=plus
|GMAF=0.2149
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=VDR
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 16.8 | 42.5 | 40.7
| HCB | 0.0 | 7.3 | 92.7
| JPT | 0.0 | 0.9 | 99.1
| YRI | 0.0 | 2.0 | 98.0
| ASW | 3.5 | 15.8 | 80.7
| CHB | 0.0 | 7.3 | 92.7
| CHD | 0.0 | 6.4 | 93.6
| GIH | 3.0 | 30.7 | 66.3
| LWK | 0.0 | 7.3 | 92.7
| MEX | 6.9 | 31.0 | 62.1
| MKK | 0.6 | 21.8 | 77.6
| TSI | 16.7 | 52.9 | 30.4
| HapMapRevision=28
}}
A very small study of 117 healthy European peri- and postmenarcheal girls (14.9 +/- 1.6 years) were followed for 4 years along with their calcium intake. Girls with [[rs4516035]](C;T) and (C;C) genotypes had 13% lower spine mineral content if their milk intakes were below 260 mL/day, compared to either genotype-matched girls with higher milk intakes or to girls with the (T;T) genotype. If this is real, it suggests that [[rs4516035]](C;T) and (C;C) female teens need more milk than [[rs4516035]](T;T) girls to have optimal bone density.

{{PMID|19105801|OA=1
}} [[rs4516035]] and the more aggressive tumour location in head-neck and trunk (OR=1.54, p=0.020)

{{PMID Auto
|PMID=18587672
|Title=Vitamin D receptor variants and breast cancer risk in the Polish population
}}
{{PMID Auto
|PMID=20046590
|Title=The unfavorable effect of the A allele of the vitamin D receptor promoter polymorphism A-1012G has different mechanisms related to susceptibility and outcome of malignant melanoma
|OA=1
}}

{{PMID Auto
|PMID=20394945
|Title=Infantile hypercalcemia and hypercalciuria: new insights into a vitamin D-dependent mechanism and response to ketoconazole treatment
}}

{{PMID Auto
|PMID=21365644
|Title=Vitamin D receptor polymorphisms in patients with cutaneous melanoma
|OA=1
}}

{{PMID Auto
|PMID=22544453
|Title=Early life sun exposure, vitamin D-related gene variants, and risk of non-Hodgkin lymphoma
|OA=1
}}

{{PMID Auto
|PMID=17130574
|Title=Protection from type 1 diabetes by vitamin D receptor haplotypes.
}}

{{PMID Auto
|PMID=18205531
|Title=Vitamin D receptor gene haplotypes and susceptibility to HIV-1 infection in injection drug users.
}}

{{PMID Auto
|PMID=19309297
|Title=Higher milk requirements for bone mineral accrual in adolescent girls bearing specific caucasian genotypes in the VDR promoter.
}}

{{PMID Auto
|PMID=19450131
|Title=Application of pharmacogenomics to vaccines.
|OA=1
}}

{{PMID Auto
|PMID=19615888
|Title=Vitamin D receptor gene polymorphisms, serum 25-hydroxyvitamin D levels, and melanoma: UK case-control comparisons and a meta-analysis of published VDR data.
|OA=1
}}

{{PMID Auto
|PMID=19679055
|Title=Vitamin D receptor variants and the malignant melanoma risk: a population-based study.
}}

{{PMID Auto
|PMID=19682379
|Title=TagSNP transferability and relative loss of variability prediction from HapMap to an admixed population.
|OA=1
}}

{{PMID Auto
|PMID=20015871
|Title=Pharmacogenetic risk factors for altered bone mineral density and body composition in pediatric acute lymphoblastic leukemia.
|OA=1
}}

{{PMID Auto
|PMID=20398755
|Title=Growth, calcium status and vitamin D receptor (VDR) promoter genotype in European children with normal or low calcium intake.
}}

{{PMID Auto
|PMID=20716226
|Title=Clinical and genetic predictors of response to narrowband ultraviolet B for the treatment of chronic plaque psoriasis.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}
{{on chip | NatGeo2}}