{{Rsnum
|rsid=4532
|Gene=DRD1
|Chromosome=5
|position=175443147
|Orientation=plus
|GMAF=0.2534
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=DRD1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 11.5 | 61.1 | 27.4
| HCB | 1.5 | 27.4 | 71.1
| JPT | 2.7 | 18.8 | 78.6
| YRI | 0.7 | 14.3 | 85.0
| ASW | 1.8 | 21.1 | 77.2
| CHB | 1.5 | 27.4 | 71.1
| CHD | 1.9 | 25.5 | 72.6
| GIH | 16.8 | 44.6 | 38.6
| LWK | 2.9 | 12.4 | 84.8
| MEX | 1.7 | 50.0 | 48.3
| MKK | 0.0 | 0.0 | 0.0
| TSI | 14.9 | 51.5 | 33.7
| HapMapRevision=28
}}Implicated as part of a haplotype of the dopamine D1 receptor [[DRD1]] gene associated with [[autism]] spectrum disorders in families having only affected males. The haplotype is [[rs265981]](C)-[[rs4532]](A)-[[rs686]](T) as published, though not necessarily as oriented in dbSNP.{{PMID|18205172}}

{{ neighbor
| rsid = 265981
| distance = 752
}}

{{omim
|desc=SCHIZOPHRENIA; SCZD
|id=181500
|rsnum=4532
}}

{{omim
|desc=TOBACCO ADDICTION, SUSCEPTIBILITY TO
|id=188890
|rsnum=4532
}}

{{omim
|desc=DOPAMINE RECEPTOR D1; DRD1
|id=126449
|rsnum=4532
}}

{{PMID Auto
|PMID=20382433
|Title=No genetic association between dopamine D1 receptor gene and [early onset] schizophrenia
}}
{{PMID Auto
|PMID=20456319
|Title=Association of polymorphisms in the BDNF, DRD1 and DRD3 genes with tobacco smoking in schizophrenia
}}

{{PMID Auto
|PMID=22093926
|Title=[Association analysis between dopamine D1 receptor gene and symptom quantitative trait of schizophrenia]
}}

{{PMID Auto
|PMID=15087492
|Title=A new approach to SNP genotyping with fluorescently labeled mononucleotides.
|OA=1
}}

{{PMID Auto
|PMID=17092969
|Title=Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response.
}}

{{PMID Auto
|PMID=18092181
|Title=Significant association of DRD1 with nicotine dependence.
}}

{{PMID Auto
|PMID=18341651
|Title=A haplotype of the DRD1 gene is associated with alcohol dependence.
}}

{{PMID Auto
|PMID=18366720
|Title=Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=21181138
|Title=Analysis of genetic variations in the dopamine D1 receptor (DRD1) gene and antipsychotics-induced tardive dyskinesia in schizophrenia.
}}

{{PMID Auto
|PMID=21955727
|Title=An association study between dopamine D1 receptor gene polymorphisms and the risk of schizophrenia.
}}

{{PMID Auto
|PMID=23036699
|Title=DRD1 rs4532 polymorphism: A potential pharmacogenomic marker for treatment response to antipsychotic drugs
}}

{{PMID Auto
|PMID=25018632
|Title=Association of dopamine D1 receptor gene polymorphism with schizophrenia: a meta-analysis
}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}